Of everything currently on the air, House is by far my favorite show.
Others I like are Law and Order (Original and SVU -- don't really like Criminal Intent)
I love Desperate Housewives, though I rarely get a chance to actually watch it.
I LOVED Kid Nation when it was on (hated the way it was produced and executed, but I thought it was really touching despite all that), though I strongly suspect that if they make another season, it won't be nearly as good.
And then there are a few cartoons/animes that I like (or rather, liked). I love Invader Zim, Megas XLR, and Rocko's Modern Life (none of which is still on). And the first couple seasons of Rugrats were pure brilliance.
As far as anime, my favorite series' are Ghost in the Shell, Wolf's Rain, Paranoia Agent, Gundam: Seed, and Samurai Champloo (I don't know if Adult Swim still shows any of these, but I have most of them on DVD anyway)